Comedian Fortune Feimster is hurtling towards a divorce … TMZ has learned.

Sources with direct knowledge tell TMZ … Fortune and her wife, Jacquelyn Smith, recently separated and Fortune is planning to file for divorce.

It’s unclear what caused the split or when they separated … but our sources say Fortune has been telling people in her orbit about the split more recently … so it sounds pretty fresh.

The estranged couple does not have any children together.

Fortune made her TV debut in 2010 on NBC’s “Last Comic Standing” … and she’s famous for her role as Colette in “The Mindy Project.” She also has acting credits on “The L Word” reboot, “The L Word: Generation Q.”

We reached out to Fortune’s camp … so far, no word back.